Author

Chang-Lei Li

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Open access Jul 2026

Antihypertensive drug targets and pancreatitis reporting signals: An integrative mendelian randomization and FAERS pharmacovigilance study

Objective To investigate whether genetically proxied antihypertensive drug targets are associated with pancreatic exocrine diseases and whether corresponding antihypertensive agents show pancreatitis-related pharmacovigilance signals. Methods This integrative genetic epidemiology and pharmacovigilance study combined li...

Chang-Lei Li, Si-Han Wang, Zhi-Yuan Yao et al. · Science in progress · 0 citations

Open access Aug 2026

Exposure to TBBPA and polystyrene nanoplastics induces cardiac fibrosis via the activation of the ESR/H19/Wnt pathway

Cardiac fibrosis is a key pathological driver of heart failure and cardiovascular mortality, with environmental pollutants being increasingly implicated. Tetrabromobisphenol A (TBBPA), a dominant brominated flame retardant (BFR), is environmentally pervasive and poses potential cardiotoxic risks. However, direct eviden...

Xiang-Yu Pei, Xi-Ran Wang, Shao-Yan Liu et al. · Redox Biology · 0 citations