NLRP3 inflammasome and Epstein-Barr virus: mutual regulation and therapeutic potential.
Epstein-Barr virus (EBV), a prevalent and virulent human γ-herpesvirus, is etiologically linked to an extensive spectrum of malignancies and autoimmune disorders. The NLR family pyrin domain-containing 3 (NLRP3) inflammasome serves as a central sensor of innate immune defense and critically modulates host-EBV crosstalk...