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Chang-Min Ding

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Open access Aug 2026

Kinase-based molecular subtyping and a prognostic risk model in colorectal cancer with functional validation of PLK4

Background Colorectal cancer (CRC) exhibits marked molecular heterogeneity, yet prognostic tools centered specifically on protein kinases remain scarce. This study aimed to identify kinase-related molecular subtypes of CRC and to develop and validate a kinase-based prognostic risk model integrating clinical and immune...

Chao-Long Shen, Chang-Min Ding, Xiao-Feng Han et al. · 0 citations

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