Integrative Genetic, Transcriptomic, and Single-Cell Analyses Prioritize Druggable Candidate Genes in Knee Osteoarthritis.
Knee osteoarthritis (KOA) is a common degenerative joint disease with a complex pathogenesis and a lack of effective molecular targets. This study aimed to prioritize druggable genes associated with KOA and investigate their expression patterns and cellular localization by integrating genetic, transcriptomic, and singl...