2026
An irinotecan nanoprodrug self-assembled from small molecules for nitroreductase-responsive drug release
Active ester-mediated strategy yields nitroreductase-responsive irinotecan nanoprodrugs via small-molecule self-assembly, enabling carrier-free targeted delivery and on-demand release in hypoxic tumors with high selectivity.
Xin-Xi Huang, Long Lin, Chang-Yu Huang et al.
· New Journal of Chemistry · 0 citations