Author

Changyuan Guo

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Open access Jul 2026

Single cell spatial transcriptomics track the evolutionary hierarchy and microenvironment remodeling during breast carcinoma invasion

A unified spatial-molecular atlas of DCIS-IBC progression is established, highlighting clonal expansion, transcriptional plasticity and TME remodeling as key drivers of invasion.

Di Wang, Qichen Dai, Jing Guo et al. · Nature Communications · 0 citations