Author

Chao-Chun Wei

h-index 6 View on Semantic Scholar

We have 2 of 26 papers

We haven’t gathered this author’s papers yet. Follow them and we’ll fetch their work.

Not the right person? Other researchers publish under this name.

Sep 2026

Identification of FLT3-ITD inhibitors through AI-guided virtual screening, biochemical validation, DFT analysis, and molecular dynamics simulation.

FLT3-ITD is a major therapeutic target in acute myeloid leukemia (AML). Herein, we developed an AI-assisted discovery workflow integrating graph neural network (GNN) modeling, virtual screening, biochemical validation, and mechanistic analysis to identify novel FLT3-ITD inhibitors. A curated dataset of 3779 compounds f...

Cong Wang, Hui-Jie Han, Xiao-Kun Zhang et al. · Bioorganic chemistry (Print) · 0 citations

Aug 2026

Dual targeting of VEGFR2 and ErbB3 by a novel quinoline derivative E5: Mechanistic insights from DFT, molecular docking and MD simulations.

A novel quinoline derivative, 7-(benzyloxy)-N-(3-chloro-2-fluorophenyl)-6-methoxyquinolin-4-amine (E5), was successfully identified as a potent dual-target inhibitor with favourable dual-target binding potency, highlighting E5 as a promising lead compound that warrants further investigation to address clinical anti-ang...

Xin-Yu Zhou, Ya-Nan Yuan, Chao-Chun Wei et al. · Computational biology and ch... · 0 citations