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Open access Oct 2026

Invasive Pneumococcal Disease in Children: A Retrospective Three-Center Study in Zhejiang Province, China (2010-2024).

INTRODUCTION Invasive pneumococcal diseases (IPD) are among the leading causes of global child mortality. Pneumococcal conjugate vaccines provide direct protection against IPD caused by serotypes included in the vaccine. OBJECTIVE To investigate the clinical characteristics, serotypes, and antibiotic resistance of St...

Yan-Yan Zhu, Jin-Si Zhou, Jin-Hong Yang et al. · 0 citations
Open access Sep 2026

Utilizing machine learning and MALDI-TOF MS platform for rapid detection of ceftriaxone-resistant nontyphoidal Salmonella

ABSTRACT Ceftriaxone (CRO) is a first-line antibiotic for pediatric nontyphoidal Salmonella (NTS) infections, but rising resistance threatens public health. Conventional antimicrobial susceptibility testing remains time-consuming, delaying treatment. Although MALDI-TOF MS enables rapid microbial identification, it lack...

Jin-Tao Xia, Jun Ren, Shi-Fu Wang et al. · 0 citations

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