SLC11A1 upregulation mediates the progression of hepatocellular carcinoma and decreased sensitivity to cisplatin by mediating macrophage M2 polarization.
BACKGROUND Dysregulated expression of Solute Carrier Family 11 Member 1 (SLC11A1) has been found to be dysregulated in multiple human cancers and is implicated in tumor progression. However, the precise functions and underlying mechanisms of SLC11A1 in hepatocellular carcinoma (HCC) remains largely unknown. METHODS T...