KRT13 Drives Pancreatic Cancer Malignancy Via the PI3K/AKT-PPARG Axis While Enhancing Sensitivity to Navitoclax.
BACKGROUND Pancreatic cancer remains one of the most aggressive malignancies, characterized by late diagnosis, limited treatment options, and a dismal prognosis, with a 5-year survival rate consistently below 13%. The molecular mechanisms driving its progression are incompletely understood, highlighting the need to ide...