Open access
Aug 2026
Kinase-based molecular subtyping and a prognostic risk model in colorectal cancer with functional validation of PLK4
Background Colorectal cancer (CRC) exhibits marked molecular heterogeneity, yet prognostic tools centered specifically on protein kinases remain scarce. This study aimed to identify kinase-related molecular subtypes of CRC and to develop and validate a kinase-based prognostic risk model integrating clinical and immune...
Chao-Long Shen, Chang-Min Ding, Xiao-Feng Han et al.
· Translational Cancer Researc... · 0 citations