Author

Chao Ma

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Open access Sep 2026

Identification of key genes and metabolites in thyroid eye disease through integrated transcriptomic and metabolomic analysis

Introduction Thyroid eye disease (TED) markedly compromises ocular function and quality of life, imposing significant healthcare and economic burdens. Present therapeutic strategies, which mainly include glucocorticoids, teprotumumab, immunosuppressive drugs, and surgical treatments, exhibit limited effectiveness and a...

Chen-Yan Fang, Qian Li, Ni-Shan Zhao et al. · Frontiers in Endocrinology · 0 citations

Open access Sep 2026

A deep learning framework for oligopeptide candidate discovery across metabolism-related contexts.

Artificial intelligence (AI)-based methods are increasingly critical in therapeutic peptide discovery but have been concentrated in certain applications, such as the development of antimicrobial peptides. Therapeutic peptide discovery in contexts such as metabolism, endocrinology, and tissue regeneration remains challe...

Bai-Chuan Xiao, Hao Zhu, Chao Ma et al. · Cell Reports Methods · 0 citations