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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Chao Wang

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Open access Aug 2026

Lactylation of USP11 fosters breast cancer development by stabilizing CDK4 and activating CDK4-RB1-E2F1 pathway

Cyclin-dependent kinase 4 (CDK4) is a key player in the cell cycle. Its frequent overexpression in a multitude of cancers correlates with increased cell proliferation and resistance to CDK4 inhibitors, highlighting the critical need to target CDK4 degradation as a therapeutic approach. However, the mechanisms governi...

Chao Wang, Siru Zhou, Yulin Li et al. · 0 citations

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