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Sep 2026

Correlational Analysis of Qiming Granule with the CMKLR1-Centered Network and Systemic Inflammation via the Gut-Retina Axis in Diabetic Retinopathy.

Preliminary pharmacological evidence is provided that QMG ameliorates DR by coupling the CMKLR1-centered regulatory network (including Wnt5a, PPAR-γ, AP-1, and TP53) and systemic inflammation via the gut-retina axis, positioning QMG as a promising gut-retina therapeutic strategy for DR.

Yun-Xi Xu, Tian-Yao Gong, Qin-Dong Mi et al. · 0 citations
Open access Sep 2026

Traditional Chinese herbal formula Huo Luo Xiao Ling Dan ameliorates rheumatoid arthritis by suppressing inflammation and oxidative stress via the AGE/RAGE/NF‑κB signaling pathway.

Rheumatoid arthritis (RA) is a chronic autoimmune pathology that arises chiefly from the dysregulated activation of fibroblast-like synoviocytes. The traditional Chinese herbal formula Huo Luo Xiao Ling Dan (HLXL) has unclear mechanisms in RA treatment. This work combined network pharmacology with both cellular and ani...

Wen-Yan Yang, Ning Yang, Chao Xu et al. · 0 citations

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