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Open access Aug 2026

Negative allosteric regulation of protein arginine methyltransferase 1 (PRMT1) through half-of-sites reactivity

Mechanistic understanding of inter-subunit communication in PRMT1 oligomers is expanded and half-of-sites reactivity is identified as a previously unrecognized regulatory feature that may be leveraged for the development of PRMT1-selective allosteric inhibitors.

Vincent Rossi, Robert S. Wilson-Kovacs, Yuan Gao et al. · 0 citations
Review Jul 2026

Decoding Cardiovascular Disease Through Spatial Proteomics.

An integrated workflow in which untargeted, whole-tissue mapping of thousands of proteins is first used to unbiasedly discover spatial patterns and generate hypotheses by identifying candidate regions and proteins of interest, followed by hypothesis testing and validation using high-precision region-of-interest-based p...

Min Ma, Yingyi Lian, Erfei Shang et al. · 0 citations

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