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Review Sep 2026

Recent Advances in the Production and Biosynthesis of Oleanane-Type Pentacyclic Triterpenoids

Oleanane-type pentacyclic triterpenoids are a class of naturally occurring specialized metabolites with diverse biological activities. Conventional plant extraction and chemical synthesis are constrained by low yields, high costs, and a reliance on natural resources. With the development of synthetic biology and meta...

Fu-Yan Yuan, De-Yue Diao, Shi-Xiang Peng et al. · 0 citations
Jul 2026

Metabolic flux reprogramming and protein engineering drive efficient l-arginine biosynthesis.

l-arginine is widely used in food, feed, pharmaceutical, and cosmetic industries. However, its industrial-scale biosynthesis is limited by insufficient coordination between metabolic regulation, pathway engineering, and fermentation optimization. In this study, an enzyme-constrained model (ec_iML1515) was used to ident...

Shengyang He, Qi Sheng, Gang Men et al. · 0 citations

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