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Chao-Zheng Zhang

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Open access Aug 2026

Spatiotemporally programmed hybrid nano-prodrugs orchestrate multidimensionally synergistic cascade lethality in NSCLC

This findings demonstrate that E-R@ISSL achieved coordinated DNA damage, ferroptosis, and ICD induction through its dual-targeted and sequentially activated co-delivery of ETP and LA, concurrently dismantling the GSH/GPX4 antioxidant defense and intensifying oxidative injury.

Yan Wang, Chao-Zheng Zhang, Chen Sun et al. · 0 citations

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