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Author

Chaoyao Hou

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Review Open access Sep 2026

The “Double-Edged Sword” of Neutrophils in Trauma: From Pathophysiological Mechanisms to Precision Immunomodulation Strategies

Neutrophils occupy a central yet paradoxical position in post-trauma immunity, functioning as both sentinels of host defense and mediators of tissue damage. This review comprehensively examines the spatiotemporal dynamics of neutrophil biology after trauma, ranging from recruitment and effector functions to diverse cel...

Chao-Yao Hou, Zhao-Feng Kang, Shuang Qin et al. · 0 citations
Review Open access Aug 2026

The Neuroimmune Axis in Sepsis: From Pathophysiological Circuits to Precision Neuromodulation

Abstract Sepsis, a life-threatening organ dysfunction caused by a dysregulated host response, is characterized by a dynamic progression from hyperinflammation to immunosuppression. Its persistently high mortality underscores the limitations of therapies focused solely on immune homeostasis. This review advocates a para...

Chuntao Wang, Xiaojiang Huang, Chaoyao Hou et al. · 0 citations

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