Bisphenol A promotes prostatic inflammatory susceptibility via PI3K/AKT-mediated mitochondrial stress and NLRP3 inflammasome sensitization.
Integrative evidence that environmental BPA exposure may contribute to increased susceptibility to prostatic inflammation under pathological conditions is provided and impaired PI3K/AKT signaling, mitochondrial oxidative stress, and NLRP3 inflammasome activation are identified as key underlying mechanisms, thereby prov...