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Charlotte Guhl

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Open access Sep 2026

Inhibitor fluorination pattern modulates protein surface dynamics and chemically induced dimerization

Chemically induced proximity is a powerful strategy to regulate cellular processes using small-molecule ligands that act as “molecular glues” to influence the lifetime, localization, and function of biological targets. However, the structure–activity relationships governing such inducible interactions remain elusive. H...

Eric Schwegler, Jean-Martin Harder, Marco D. Preuss et al. · 0 citations

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