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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

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Chen Chen

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Open access Oct 2026

Joint associations of cardiovascular-kidney-metabolic syndrome and depressive symptoms with incident frailty: the mediating role of body roundness index

Frailty is a multidimensional geriatric syndrome associated with increased vulnerability to adverse outcomes in aging populations. Both cardiovascular-kidney-metabolic (CKM) syndrome and depressive symptoms have been independently linked to frailty, but their combined associations and underlying pathways remain u...

Shou-Chuang Zhang, Jia Tang, Chen Chen et al. · 0 citations

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