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Caffeic acid alleviates osteoarthritis progression by suppressing ferroptosis-associated injury and modulating the ACSL4-GPX4 axis
Background: This study explores the protective effects of caffeic acid (CA) on chondrocytes and its mechanisms in mitigating osteoarthritis (OA) progression. Methods: We investigated the effects of CA on OA progression in a monosodium iodoacetate (MIA)-induced rat OA model and IL-1β/Erastin-stimulated C28/I2 chondrocyt...
Pan-Wen Tu, Yu-Xin Zhou, Wei-Li Yan et al.
· Traditional Medicine Researc... · 0 citations