Open access
Sep 2026
Radiosynthesis and preclinical evaluation of 4-N-[¹⁸F]FDG-PBA as a novel PET tracer for tumor imaging
Conventional [¹⁸F]FDG exhibits inherent drawbacks in liver tumor imaging, especially high physiological uptake in normal hepatic tissues, which severely compromises the diagnostic accuracy of hepatic tumors. To address these limitations, we synthesized a novel tracer, 4-N-[¹⁸F]FDG-PBA, via conjugation of [¹⁸F]FDG...
Wei-Xuan Dong, Cong Shen, Ru-Xi Chang et al.
· EJNMMI Radiopharmacy and Che... · 0 citations