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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

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Chen-Qiu You

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Open access Oct 2026

scTIME: single-cell-informed interpretable modeling of immunotherapy-associated immune states in non-small cell lung cancer

Immune checkpoint inhibitor response in non-small cell lung cancer (NSCLC) reflects coordinated tumor and immune states that are not fully captured by single biomarkers. We developed scTIME, an interpretable model that translates single-cell immune programs into bulk transcriptomic scores, and integrated public singl...

Guo-Zhi Chen, Chen-Qiu You, H.-O. Gao et al. · 0 citations

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