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Author

Chen Wang

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Open access Aug 2026

Sodium Rutin Alleviates Neuronal Apoptosis and Promotes Locomotor Recovery in Distractive Spinal Cord Injury via ErbB4 and ROS Signaling.

BACKGROUND Distractive spinal cord injury (DSCI), a severe complication of spinal deformity correction surgery, is characterized by rapid neuronal loss. However, the molecular mechanisms linking mechanical distraction to apoptosis remain unclear. Here, we tested whether sodium rutin (NaR), a water-soluble rutin derivat...

Wei-Shi Liang, Ye-Qiu Xu, Junrui Jonathan Hai et al. · 0 citations
Open access Aug 2026

Isorhoifolin regulates S1PR3-CK2-GSK3β axis and promotes neurite regrowth and functional recovery after traumatic brain injury.

A neuron-centric role for S1PR3 in regulating structural repair is delineated that is mechanistically distinct from the known functions of S1PRs in immune cells and defines mechanistically distinct yet coordinated neuronal and astrocytic pathways that are responsible for isorhoifolin-enhanced structural and functional...

Yi Wang, Wen-Lin Liao, Chen Wang et al. · 0 citations

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