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The RPA-CRISPR/Cas12a system established in this study exhibits high specificity, ultra-sensitivity and operational simplicity, making it a promising tool for rapid and field-deplorable detection of ChCV.
Investigating the antiviral potential of baicalin in epithelioma papulosum cyprini cells and zebrafish demonstrates that baicalin significantly suppresses SVCV replication and is associated with modulation of the AMPK/mTOR-mediated autophagy pathway.
These findings provide the first evidence that the T7SS influences magnesium homeostasis and is essential for maintaining capsule integrity, both of which contribute critically to pathogenicity.
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