TL1A promotes microglial inflammatory response via DR3-NF-κB signaling to mediate the progression of postoperative cognitive dysfunction.
AIM To investigate the mechanism by which tumor necrosis factor ligand-related molecule 1 A (TL1A) promotes the progression of postoperative cognitive dysfunction (POCD). METHODS A POCD mouse model was established by splenectomy. Cognitive and behavioral abilities of mice were assessed using the Morris water maze, op...