CRISPR Screening Advances Drug Target Discovery in Cancer and Neurodegenerative Diseases: From Preclinical Research to Clinical Translation — A Literature Review
CRISPR/Cas9 technology enables genome-scale functional screening to identify genetic dependencies in cancer and neurodegenerative diseases (NDs) research. This review compares and contrasts how CRISPR screenings advance drug target discovery and clinical applications in both research fields. Literature search was condu...