Vibrio harveyi is a major bacterial pathogen in marine aquaculture, posing a serious threat to fish health. IRF1 is a conserved regulator of teleost immunity; however, the transcriptional regulatory networks associated with IRF1 during bacterial infection remain incompletely understood. To characterize CaIRF1-associate...
Guo-Tao Wang, Gui-Sen Chen, Ting Wu et al.· Developmental and Comparativ...· 0 citations
Bok (Bcl-2-related ovarian killer) is a pro-apoptotic member of the Bcl-2 family that plays a critical role in the intrinsic apoptotic pathway in mammals. However, its functional characterization in teleost fish remains largely unexplored. In this study, we identified and characterized TroBok, a Bok ortholog from golde...
Zhen-Jie Cao, Zhi-Ru Liu, Jing Zhang et al.· Fish and Shellfish Immunolog...· 0 citations
These results validated the canonical heterodimerization of the short-chain CaCRFB5 with both long-chain subunits (CaCRFB1 and CaCRFB2) as well as a noncanonical interaction of CaCRFB1/CaCRFB2, suggesting a more intricate receptor pairing in teleosts.
Han Zhang, Ting Wu, Ying Chen et al.· Developmental and Comparativ...· 0 citations
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