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Open access Sep 2026

Profiling proteome-level amino acid substitutions in Alzheimer’s disease brain tissue

As the most prevalent neurodegenerative disorder worldwide, Alzheimer’s disease (AD) remains incompletely understood at the proteome level. In particular, current studies on amino acid (AA) substitutions have predominantly relied on genomic and transcriptomic profiling. Proteome-scale AA substitutions remain largely un...

Pei-Ze Zhao, Sheng-Zhi Lai, Shuai-Jian Dai et al. · 0 citations

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