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Author

Cheng Chen

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Open access Jul 2026

Single-cell lineage tracing of human neuromesoderm organoids reveals TBX6-mediated posterior mesoderm fate diversification

A CRISPR/Cas9-based single-cell lineage tracing system with paired multiomics profiling in human pluripotent stem cell-derived neuromesodermal organoids to reconstruct high-resolution lineage relationships spanning 50 days of differentiation provides a clonal-resolution lineage map of human NMP differentiation and adva...

Yuanxin Liao, Cheng Chen, Meisi Li et al. · 0 citations

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