Author

Cheng-Cheng Xu

2 papers indexed here

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Open access Jul 2026

Prediction of the clinical outcomes of imipenem and meropenem in patients with treatment-associated AKI and death via machine learning models combined with pharmacokinetic parameters: A retrospective cohort study

Objective The present study aimed to develop and evaluate machine learning-based predictive models for acute kidney injury (AKI) and all-cause mortality in patients treated with imipenem or meropenem, integrating pharmacokinetic (PK) parameters with routine clinical features. Methods A total of 235 patients who receive...

Yun Chen, Dan-Lin Zheng, Cheng-Kuan Zhao et al. · Science in progress · 0 citations

Open access Aug 2026

Extracellular vesicles from human adipose-derived mesenchymal stem cells reprogram macrophage lipid metabolism via the ABCF1/CPT1A/IL-10 axis to mitigate sepsis-induced acute lung injury

Sepsis-induced acute lung injury (ALI) is a life-threatening syndrome characterized by overwhelming inflammation, immune dysregulation, and tissue damage. Metabolic reprogramming of macrophages has emerged as a central regulator of inflammatory responses. Extracellular vesicles (EVs) derived from mesenchymal stem cel...

Ling-Yu Zhang, Dainian Guo, Qing-Xuan He et al. · Cell Death Discovery · 0 citations