Oct 2026
ST3GAL1-mediated α-2,3 sialylation restrains CD105-TGFβRII signaling to attenuate EndMT-driven atherosclerosis.
BACKGROUND AND AIMS Endothelial-to-mesenchymal transition (EndMT) contributes to atherosclerotic plaque progression. Although endothelial sialylation is essential for vascular homeostasis, its role in EndMT remains poorly understood. This study investigated the role and underlying mechanism of α-2,3 sialylation in EndM...
Tian-Lan Xi, Qian Liu, Yu-Mei Dai et al.
· Atherosclerosis · 0 citations