Author

Cheng-Long Yu

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Open access Aug 2026

Circulating biomarkers and polygenic scores for cardiovascular risk prediction in healthy older adults: differential and complementary contributions.

BACKGROUND AND AIMS Atherothrombotic cardiovascular disease (CVD) risk prediction in older adults remains suboptimal. The relative contributions of circulating protein biomarkers and polygenic scores (PGS) are uncertain. METHODS In 10,433 older individuals aged ≥70 years without prior CVD events, we evaluated traditi...

Cheng-Long Yu, C. Tran, J. Neumann et al. · Atherosclerosis · 0 citations

Open access Aug 2026

Triglyceride Polygenic Score Identifies Individuals Who May Respond Differently to Aspirin in Primary Prevention

The hypothesis‐generating findings suggest triglyceride‐related genetic variation may identify individuals with differential responses to aspirin, and suggest triglyceride‐related genetic variation may identify individuals with differential responses to aspirin.

P. Fransquet, Cheng-Long Yu, C. Tran et al. · Clinical pharmacology and th... · 0 citations

Open access Jul 2026

Diet quality and depressive symptoms in older adults, assessing the effect modification by genetic predisposition and low-grade inflammation: a target trial emulation.

Higher diet quality is associated with a lower risk of depressive symptoms, independent of genetic predisposition or low-grade inflammation, which may support dietary interventions as a modifiable lifestyle strategy for mental health promotion and prevention in older adults.

Belayneh Mengist, Najmeh Davoodian, M. Lotfaliany et al. · Molecular Psychiatry · 0 citations