Cheng Ouyang

Rational Design of Lysosome-Targeted Iridium(III) Complex for HClO Imaging and Monitoring Drug-Induced Bidirectional HClO Dynamics

A series of Ir(III) complexes targeting lysosomes and bearing an imino ortho phenylene HClO recognition unit was developed for selective HClO imaging. In these probes, electrophilic addition triggered by HClO at the recognition unit modulates emission from the Ir(III) coordination core, representing the first use of...