Author

Cheng-Sheng Mao

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Open access Jul 2026

CAR T cell foundation model predicts immunotherapy response

Single-cell transcriptomics resolves CAR T-cell states, yet translating heterogeneous cellular signals into patient-level therapeutic response remains challenging. Existing studies primarily identify response-associated genes or cell populations through experimental and statistical analyses, but few predictive framewor...

Yawei Li, De-Yu Fang, Cheng-Sheng Mao et al. · bioRxiv · 0 citations

Conference Open access Sep 2026

Hierarchical Conditional Energy Modeling for Medical Vision–Language Pretraining

HCE-CLIP is proposed, a vision–language pretraining framework that formulates medical image–text alignment as a hierarchical label-conditional energy modeling problem and introduces a hierarchical contradiction-based metric that quantifies logical inconsistencies between fine-grained disease predictions and higher-leve...

Cheng-Sheng Mao, Yuan Luo · Proceedings of the Thirty-Fi... · 0 citations