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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Cheng Wang

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2 papers indexed here

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Sep 2026

Panaxytriol up-regulates CYP2B6 expression through PXR and CAR and their interactions with RXRα and SRC-1.

ETHNOPHARMACOLOGICAL RELEVANCE Cytochrome P450 2B6 (CYP2B6) is a critical drug-metabolizing enzyme, and its expression is regulated by the nuclear receptors. Panaxytriol (PXT), a prominent bioactive constituent extracted from the roots of Panax ginseng C.A. Meyer, was found to induce cytochrome P450 3A4 (CYP3A4) via pr...

Lin Huang, Yin-Yue Du, Qi Gu et al. · 0 citations
Open access Aug 2026

Schisandrin B protects against oxaliplatin-induced liver injury by suppressing ferroptosis via the canonical KEAP1-Nrf2 and non-canonical microbiota-driven Lactobacillus reuteri-CLA-Nrf2 axes.

Ferroptosis is a critical contributor to chemotherapy-induced liver injury. Schisandrin B (SchB), a bioactive compound from Schisandra chinensis, exerts hepatoprotection, but the underlying mechanisms in oxaliplatin (OXA)-induced liver injury are unclear. In this study, OXA treatment induced hepatic dysfunction, lipid...

Ping Huang, Shanji Li, Yichen Liu et al. · 0 citations

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