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Cheng-Xin Zhang

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Open access Sep 2026

Short- and mid-term outcomes of mitral valve repair vs. replacement in degenerative mitral regurgitation with left ventricular enlargement

Objective This study evaluates short- to mid-term outcomes following mitral valve repair (MVP) and mitral valve replacement (MVR) among patients with degenerative mitral regurgitation (DMR) complicated by substantial left ventricular dilatation (LVD). Methods We performed a retrospective analysis enrolling 150 patients...

Chun Wu, Zhe Sheng, Jian-Hao Hu et al. · 0 citations
Open access Jul 2026

The Role of Cysteine-Rich Protein 2 in Aortic Dissection: Implications for VSMC Phenotypic Modulation—CSRP2 Impedes the Progression of Aortic Dissection

Findings identify CSRP2 as a novel regulator of VSMC phenotypic modulation and a significant modulator of AD development, suggesting its potential as a target for early intervention for AD.

Can Liu, Xiangyu Wang, Cheng An et al. · 0 citations
Open access Aug 2026

Predicting in-hospital mortality after cardiac surgery using machine learning: temporal validation in the MIMIC-IV database

Background Machine learning (ML) models have been increasingly applied to surgical risk prediction; however, their comparative performance and temporal generalizability remain inadequately evaluated. Methods A retrospective cohort study of 9,956 adult patients undergoing coronary artery bypass grafting and/or valve sur...

Jian-Hui Zhou, Cheng-Xin Zhang · 0 citations

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