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Open access Oct 2026

FGF-23 is associated with increased risk of abdominal aortic calcification

Fibroblast growth factor 23 (FGF23) is involved in the regulation of phosphate metabolism and has been linked to vascular calcification. However, the genetic association between FGF23 and abdominal aortic calcification (AAC) remains unclear. We conducted a bidirectional two-sample Mendelian randomization (MR) study to...

Lei Song, Juan Chen, Cheng Xue et al. · 0 citations
Open access Sep 2026

Perspectives on the Nutritional Paradox in Uremia: A “Sensitize-Then-Feed” Framework for Protein-Energy Wasting

A model in which gut-microbiome–derived uremic toxins, notably tryptophan metabolites, have been shown in experimental models to impair the blood–brain barrier integrity is proposed, and a translational “sensitize-then-feed” therapeutic paradigm is advocated.

Mao-Ting Li, Ze-Wei Chen, Nan-Mei Liu et al. · 0 citations

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