Cheng Zhang

Pd-Catalyzed Regio‑, Diastereo‑, and Enantioselective Construction of Vicinal Tertiary Stereocenters from Cyclic Allylboronate Salts and Allyl Electrophiles

A regio-, diastereo-, and enantioselective Pd-catalyzed allylation of the lithium salts of 6-membered cyclic allylboronates is reported. The system relies on the use of a commercially available C 2-symmetric chiral bisphosphine ligand and gives access to borylated 1,5-dienes featuring vicinal 3,4-cis tertiary stereocen...