Jul 2026
Improving expression of Photobacterium sp. JT-ISH-224 α2,6-sialyltransferase using ProteinMPNN and machine learning guided combinatory mutagenesis
The potential of machine learning–assisted protein engineering is demonstrated and an α2,6-SiaT variant with high expression levels for the biological synthesis of 6′-SL is provided.
Qingshi Wen, Huang Li, Weiyi Wang et al.
· Biotechnology Letters · 0 citations