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Sex-stratified associations between depressive symptoms and cognitive impairment in treatment-resistant vs. non-resistant schizophrenia.
Integrated proteomics and network pharmacology reveal autophagy-lysosomal regulation underlying sulforaphane-mediated neuroprotection in Alzheimer's disease.
INTRODUCTION Alzheimer's disease (AD) is a multifactorial neurodegenerative disorder characterized by amyloid-β (Aβ)-mediated neurotoxicity, impaired autophagy-lysosomal function, and neuronal apoptosis. Although sulforaphane (SFN) has demonstrated neuroprotective properties, its molecular actions against Aβ-related ne...
Altered right amygdala-prefrontal connectivity is associated with symptom severity in major depressive disorder: An exploratory analysis of anxiety subgroups.
The findings identify disrupted right amygdala-MFG connectivity as a potential neural correlate of symptom heterogeneity in MDD, particularly in patients with anxiety symptoms.