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Chenguan Jiang

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Open access Aug 2026

Direct Substantia Nigra Deep Brain Stimulation in Parkinson's Disease: Efficacy, Safety, and the Frequency-Response Relationship.

Direct SN stimulation produced a clear frequency-dependent acute response in PD, with 130 Hz yielding the strongest motor and spatial gait benefits among the tested frequencies and effects of similar magnitude to standard STN stimulation.

Yu-Ye Liu, Chenguan Jiang, Bing-Xin Li et al. · 0 citations

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