Author

Chenyu Zhang

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Open access Jul 2026

Immunotherapeutic control of MHC I-heterogeneous tumors to minimize therapy resistance 2307892

It is demonstrated for the first time in a controlled setting with mixed MHC I+/- tumors that anti-PD-1 therapy selects for outgrowth of MHC I-deficient tumor cells, dependent on CD8 T cells.

Abigail Mende, Sooyun Cho, Chenyu Zhang et al. · Journal of Immunology · 0 citations