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Open access Aug 2026

Unveiling the inflammatory link: integrated analysis identifies BMP7 and PPBP as key genes in obstructive sleep apnea-related atrial fibrillation

Background Obstructive sleep apnea (OSA) is an independently modifiable risk factor for atrial fibrillation (AF). However, the molecular mechanism of OSA-related AF is elusive. This study aims to identify the key genes and pathophysiological changes underlying OSA-related AF. Methods Three AF expression datasets, along...

Feng Li, Xing Xu, Yi-Qi Hu et al. · 0 citations
Review Open access Aug 2026

Integrin α4β7: Pathogenic Roles in Metabolic and Inflammatory Diseases and Translational Therapeutics

This review systematically summarizes the structural characteristics, ligand interactions, and conformational regulation of α4β7, with an emphasis on its pathogenic roles in inflammatory bowel disease, cardiovascular diseases, diabetes, liver disorders, autoimmune diseases, gastrointestinal malignancies, HIV infection,...

Yue Chen, Yong Chen, Zhi-Yuan Zhang et al. · 0 citations

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