Author

Chia-Wen Tsai

3 papers indexed here

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Open access Aug 2026

MMP-2 rs243865 Polymorphism as a Risk Modifier of Hepatocellular Carcinoma in Taiwanese Males, Smokers and Alcohol Consumers

Background/Aim: Hepatocellular carcinoma (HCC) is one of the leading causes of cancer-related mortality worldwide. Matrix metalloproteinase-2 (MMP-2) plays an important role in extracellular matrix remodeling and HCC progression. This study investigated the associations of two functional MMP-2 promoter polymorphisms, r...

Te-Cheng Yueh, Ming-Hsien Wu, Mei-Due Yang et al. · Anticancer Research · 0 citations

Open access Oct 2026

Genetic Association of MMP-13 rs2252070 and rs478927 Polymorphisms With Childhood Acute Lymphoblastic Leukemia in Taiwan

Background/Aim: Matrix metalloproteinase-13 (MMP-13) plays an important role in extracellular matrix remodeling and has been implicated in the susceptibility and progression of several malignancies. However, the contribution of MMP-13 genetic polymorphisms to childhood acute lymphoblastic leukemia (ALL) remains unknown...

Pei-Chen Hsu, Chung-Lin Tsai, Jen-Sheng Pei et al. · Anticancer Research · 0 citations

Open access Oct 2026

Interleukin-4 Genetic Polymorphisms Predict Susceptibility to Childhood Acute Lymphoblastic Leukemia

Background/Aim: Interleukin-4 (IL-4) is a key T-helper 2 cytokine involved in immune regulation, allergic responses, and hematological malignancies. Although aberrant IL-4 expression has been implicated in acute lymphoblastic leukemia (ALL), the contribution of IL-4 genetic polymorphisms to childhood ALL susceptibility...

Chao Chen, Jen-Sheng Pei, Wei-Ching Chien et al. · Anticancer Research · 0 citations