Author

Chiao-Wen Lin

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Review Open access Oct 2026

Targeting oral cancer with curcumin and its structural analogs: molecular mechanisms, pharmacokinetic optimization, and clinical translation.

Curcumin is a naturally occurring polyphenol extracted from turmeric (Curcuma longa) and is known for its diverse biological functions, such as antioxidant, anti-inflammatory, anti-migratory, and anticancer activities. However, its use in clinical cancer treatment remains constrained due to challenges like limited abso...

Shih-Chi Su, Chun-Wen Su, Chia-Yi Lee et al. · Archives of pharmacal resear... · 0 citations

Open access Sep 2026

Associations of HMGA2 single-nucleotide polymorphisms with clinicopathological features of tongue squamous cell carcinoma in Taiwanese men with distinct lifestyle-related risk factors

Background Oral squamous cell carcinoma (OSCC) is a predominant malignancy of the oral cavity, with tongue squamous cell carcinoma (TSCC) accounting for a substantial proportion of cases worldwide. High-mobility group A protein 2 (HMGA2) is a nonhistone chromatin-binding factor implicated in aggressive malignant phenot...

Yi-Chieh Yang, Chia-Hwa Lee, Yi Ding et al. · Journal of Cancer · 0 citations

Open access Aug 2026

Impact of IL31RA Genetic Variants and Expression on Metastatic Progression in Oral Cavity Squamous Cell Carcinoma

IL31RA polymorphisms may be associated with an increased propensity for lymph node involvement, particularly in gingival cancer, suggesting that IL31RA may have potential clinical relevance in OCSCC progression.

Hsueh-Ju Lu, Chiao-Wen Lin, Chun-Yi Chuang et al. · Oncology Research · 0 citations