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Author

Ching-Lu Chen

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2 papers indexed here

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Review Open access Oct 2026

Context- and Cell-Dependent Roles of S1PR1 in Atherosclerosis: Therapeutic Implications of Selective S1PR1 Modulation

Sphingosine 1-phosphate receptor 1 (S1PR1) regulates vascular homeostasis and immune function, but its role in atherosclerosis has remained controversial because activating the same receptor produces divergent effects across cell types. This review synthesizes evidence on S1PR1 signaling in endothelial cells, macrophag...

Thang Nguyen Ngoc, Shih-Chang Hsu, Ching-Lu Chen et al. · 0 citations
Open access Sep 2026

Oral sodium butyrate alleviates motor deficits and dopaminergic neuronal loss in 6-hydroxydopamine-induced Parkinson’s disease rat model

This model indicates the therapeutic potential of oral NaB and provides a translational framework for investigating the mechanisms of NaB therapy in PD and associated neurological disorders and alleviated motor and non-motor deficits in rats with 6-OHDA-induced PD.

Shun-Tai Yang, Yang-Ching Chen, Tzu-Jen Kao et al. · 0 citations

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