Unlocking Microbial Access to Amino-substituted 4-Hydroxycoumarin Derivatives via Enzymatic Promiscuity and Metabolic Engineering.
Coumarins and their derivatives possess diverse bioactivities and broad applications in pharmaceuticals, food additives, and materials science. For example, amino-functionalized coumarin derivatives hold significant promise for the development of novel functional materials and drug discovery. However, the microbial bio...