Chong Gao

Immunological dysregulation of follicular helper T cells, follicular regulatory T cells, and follicular cytotoxic T cells is associated with disease activity and identifies exploratory immune patterns in rheumatoid arthritis

Background The onset and progression of rheumatoid arthritis (RA) are linked to autoantibody production driven by dysregulated germinal center (GC) responses. Follicular helper T cells (Tfh), follicular regulatory T cells (Tfr), and follicular cytotoxic T cells (Tfc) are important components of follicular immune regula...